When people go all drama queen on me, I just wait until they're done and ask, "So, what'll fix this up for ya?"
Force them to tell you what they want rather than what pisses them off. Most of the time they don't want anything but they don't realize it until they've been asked. When they realize it they tend to diffuse themselves.
Yes. That can be a problem when you're dealing with women - no offense - as they tend to think differently about "issues."
Men, generally, need to fix things. Some things can't be fixed.
Women don't necessarilly need a solution to a problem, just a channel to vent about it.
That leads to an anwser I often get to my queston above: "I just needed to vent. That's all."
My answer is usually, "Well, you just did that all over me. I'm glad I could help. If there's anything else, let me know."
The point is: Don't get sucked into their drama. You just end up with another pissed off person - you.