First up, I will say that I picked up a half a second in the quarter by going from a Holley to a QuadraJet on my Trans Am. I also picked up about 7MPG on the highway with a bigger carb.
I have had great luck with both the Q-Jet and the ThermoQuad, and as carbs go they're really my favorites. I think part of the rep they get is from people that don't know how to tune them, which is actually pretty simple on either carb. I made tons of money back in the '90s tuning "Quadra-Junks" because guys had no idea how to get rid of the hesitation. Either carb, properly adjusted, is just awesome assuming the metering rods and jets are right for the engine. The problem you run into with them is tuning parts. I used a '71 or '72 Olds 455 W-30 carb on my 400 Trans Am, and that sucker was literally perfect once I made some minor adjustments. A '75 360 ThermoQuad was equally awesome on my '84 Fifth Avenue once I got rid of the Lean Burn and stuck a 340 distributor in it and a Performer intake I had lying around that was not nice enough to sell (about a year after I sold the car, the thermostat fell into the water crossover

).
I like Holleys, but they're actually so adjustable that most guys don't know how to get them right. The adage around here was always, "You can make a Holley run well on the street or run well on the track, but not both." Really? Ever change your pump cam? Do you even know how to size your power valve? Are your accelerator-pump squirters the right size? How'd you figure out your jetting? What air bleeds have you got? What vacuum-secondary spring are you running? Blank stares every time.
I am not a fan of Carter/Edelbrock carbs with the exceptions of the ThermoQuad and the original AVS. The AFB/Performer always seems to run well right out of the box, but the counterweighted air valve has always been an issue. You simply can't make the secondary air doors open more quickly without tricky mods to the counterweights, and if you overdo it, buy a new one and start over. The Edelbrock Thunder Series AVS (simply an AFB with an adjustable air valve, virtually nothing interchanges with an OEM AVS) is definitely an improvement. I have had several Performer carbs apart that had rust in them because they sat with fuel in them for awhile, and Edelbrock puts flimsy steel float baffles in them. The rust goes right into the metering circuit, and good luck getting it out. Trying to get rust off aluminum is like trying to scrub stink off shit. I've tossed at least three in the scrap heap due to this problem.
The wildcard is the spread-bore factory-replacement Holleys (4165s). All the tuneability of a regular Holley with the fuel economy of the Q-Jet or TQ. They're a hard carb not to love if you know your way around a Holley. They're available in both vacuum and mechanical secondaries.
The absolute
last carburetor I would choose would be an AFB-style anything... I don't care how nice it is for "bolt on and go", but then again I'm not building a street rod just for looks with a 350 Chevy in it, either.